Full refund if prescription not approved
FDA-approved · Licensed physicians · All 50 states

Your nicotine-free
life starts today.

The prescription that finally makes quitting feel possible.

Respiro connects you with a licensed physician who can prescribe varenicline — the most clinically effective nicotine cessation medication available. For cigarettes, vaping, pouches, and more. Delivered to your door.

You're in. We'll be in touch soon. ✦
No commitment Full refund if not approved Cancel anytime
Licensed physicians
HIPAA compliant
FDA-approved medication
Fast delivery
44%
Abstinent at 12 weeks vs 3–5% cold turkey
More effective than nicotine patches or gum
24hr
Estimated physician review time
$0
Refund if your prescription isn't approved
The difference

Life with nicotine.
Life without it.

Right now
×Planning your day around your next hit
×Waking up already thinking about it
×The guilt after every relapse
×$2,000+ a year on nicotine
×Hiding it from people you love
×Knowing you should quit but not knowing how
12 weeks from now
Mornings that feel genuinely clear
Hours go by without a single craving
The quiet pride of actually doing it
$2,000 back in your pocket every year
Nothing to hide from anyone
You figured out how
Who it's for

Whatever your habit —
varenicline works.

Cigarette smokers
Years of packs. Failed attempts. A different approach.

Varenicline was built for you. It targets the same receptors cigarettes activate — taking the pleasure out of smoking while keeping withdrawal manageable. Many patients find it more manageable than they expected.

Vapers
Your Juul became a shadow. Time to lose it.

Vaping delivers nicotine faster and more efficiently than cigarettes. That makes the habit feel seamless — and the dependency real. Varenicline doesn't care how the nicotine gets in. It works at the receptor level.

Pouch users
Clean and discreet doesn't mean not addicted.

Zyn and similar pouches are engineered for high absorption. No smoke doesn't mean no problem. The nicotine receptor is the nicotine receptor — and varenicline reaches it regardless of how you use.

How it works

Three steps.
Twelve weeks.
A completely new chapter.

Step 01
Tell us about yourself

A 5-minute intake covering your nicotine history, medical background, and goals. Cigarettes, vaping, pouches — all welcome. Completely private. No phone call required.

About 5 minutes
Step 02
A physician reviews your case

A licensed physician reviews your intake within 24 hours. If varenicline is appropriate for you, they issue your prescription. No video call unless you prefer one.

Typically within 24 hours
Step 03
Medication arrives at your door

Your first month ships directly to you. Refills are automatic. Your physician sets your protocol. Most patients notice reduced cravings within the first week.

Delivery included · estimated 3–5 days
The science

Why varenicline
actually works.

Nicotine hijacks your brain's dopamine system. Every hit reinforces the loop. Varenicline breaks the loop at its source — binding to the same receptors nicotine targets, delivering just enough signal to quiet cravings, while blocking nicotine from delivering its usual reward.

Over 12 weeks, your brain relearns what normal feels like. No nicotine required.

12-week abstinence rates · Published clinical trials
Varenicline (Respiro) 44%
Nicotine patches / gum 16%
Cold turkey 3–5%
Sources: Published phase III clinical trials for varenicline vs NRT and placebo. Individual results may vary.
More effective than nicotine replacement
Head-to-head vs patches, gum, and lozenges in clinical trials
More effective than other Rx options
Outperforms bupropion as a standalone cessation therapy
FDA
Approved, generic, and safe
Available since 2006. Black box warning removed 2016. WHO Essential Medicines list since 2021.
12wk
Standard treatment protocol
Most patients notice reduced cravings in week one. Optional 12-week maintenance phase available.
"Varenicline is the most effective pharmacotherapy for smoking cessation, with quit rates significantly higher than nicotine replacement or placebo in head-to-head clinical trials."
Published clinical research · Phase III trials · Varenicline vs NRT and placebo
30 million reasons

America is ready
to quit nicotine.

Be among the first through the door
Launching soon across all 50 states — join the waitlist now
Early Access
30M+

Nicotine users in the United States actively looking for a way out — across cigarettes, vaping, and pouches.

CDC · 2024
National Center for Health Statistics
70%

Of current smokers say they want to quit. Most have tried and failed with patches, gum, or cold turkey alone.

CDC · 2024
Behavioral Risk Factor Surveillance
$1.8B

Global varenicline market in 2025, growing at 6.6% annually — driven by telehealth access and generic availability.

Market Research · 2025
Global Varenicline Market Report
Simple pricing

No surprises.
No hidden fees.

Step 1 · One time
$75
Consultation fee · includes physician review
  • Licensed physician review within 24hrs
  • Personalized quit protocol
  • Prescription issued if appropriate
  • Ongoing physician messaging access
Full refund if prescription not approved
Our promise
Full refund if not approved.

If a Respiro physician reviews your intake and determines varenicline isn't right for you, we refund your $75 in full. No questions. Varenicline isn't for everyone — some medical histories require alternatives. We'd rather tell you honestly than take your money.

Common questions

Everything you
want to know.

Yes. Varenicline targets nicotine receptors in the brain, not the delivery method. Whether you smoke, vape, or use nicotine pouches, the medication works the same way. Our intake is built for all forms of nicotine use.
No. You start varenicline one week before your chosen quit date, and you set that date yourself. Your physician will help you plan the timeline. Many patients find the quit date becomes obvious once cravings naturally fade in the first two weeks.
The most common are mild nausea (usually weeks one and two), vivid dreams, and occasional headaches. Taking the medication with food significantly reduces nausea. Most patients find side effects manageable and they improve after the first two weeks. Your physician will discuss this with you during review.
Varenicline previously carried a black box warning about mood changes. The FDA removed that warning in 2016 after a large clinical trial (EAGLES) found no significant increase in neuropsychiatric events versus placebo. It's been on the WHO Essential Medicines list since 2021. Your physician reviews your full history before prescribing.
You receive a full refund of your $75 consultation fee. Varenicline isn't appropriate for everyone — patients with certain seizure histories or severe kidney conditions may need different approaches. We'll tell you clearly and suggest alternatives where possible.
Yes, anytime before your next billing date. No cancellation fees, no friction, no runaround. You can pause, cancel, or restart whenever it works for you.
Ready when you are

Your nicotine-free
life starts here.

Join the waitlist. Launching soon across all 50 states. Be among the first through the door.

You're on the list. Something good is coming. ✦

No spam. Just a note when we're ready for you.